In vivo NMR imaging : methods and protocols /
Nuclear magnetic resonance imaging represents a technique that is indispensable in every day biomedical diagnostics. Thanks to the numerous ways to manipulate and detect an NMR signal, it is possible to obtain a variety of information with excellent spatial and temporal resolution. Today's MRI...
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| Language: | English |
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New York :
Humana : Springer,
©2011
Totowa, NJ : Humana Press, 2011 |
| Series: | Methods in Molecular Biology, Methods and Protocols,
771 Methods in molecular biology (Clifton, N.J.) ; v. 771 Springer Protocols (Springer-12345) |
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| 245 | 0 | 0 | |a In vivo NMR imaging : |b methods and protocols / |c edited by Leif Schroder, Cornelius Faber |
| 260 | |a New York : |b Humana : |b Springer, |c ©2011 | ||
| 264 | 1 | |a Totowa, NJ : |b Humana Press, |c 2011 | |
| 300 | |a 1 online resource (XIII, 753 pages) : |b 235 illustrations, 10 illustrations in color | ||
| 300 | |a 1 online resource (xiii, 753 pages) : |b illustrations | ||
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| 490 | 1 | |a Methods in Molecular Biology, Methods and Protocols, |x 1064-3745 ; |v 771 | |
| 490 | 1 | |a Methods in molecular biology ; |v v. 771 | |
| 504 | |a Includes bibliographical references and index | ||
| 505 | 0 | |a Physical Basics of NMR -- Spatial Encoding - Basic Imaging Sequences -- Basic Contrast Mechanisms -- Scanner Components -- Small Animal Preparation and Handling in MRI -- Cerebral Perfusion MRI in Mice -- High Field Diffusion Tensor Imaging in Small Animals and Excised Tissue -- The BOLD Effect -- Screening of CEST MR Contrast Agents -- Hyperpolarized Noble Gases as Contrast Agents -- Hyperpolarized Molecules in Solution -- MR Oximetry -- MRI using Intermolecular Multiple-Quantum Coherences -- Experimental Stroke Research: The Contributions of In vivo MRI -- Volumetry and Other Quantitative Measurements to Assess the Rodent Brain -- Models of Neurodegenerative Disease - Alzheimer's Anatomical and Amyloid Plaque Imaging -- MRI in Animal Models of Psychiatric Disorders -- Spectroscopic Imaging of the Mouse Brain -- Spinal Cord - MR of Rodent Models -- Assessment of Cardiac Function -- Plaque Imaging in Murine Models of Cardiovascular Disease -- Interventional MRI in the Cardiovascular System -- MR for the Investigation of Murine Vasculature -- MRI of the Lung: Non-invasive Protocols and Applications to Small Animal Models of Lung Disease -- Characterization of Tumor Vasculature in Mouse Brain by USPIO Contrast-enhanced MRI -- Cancer Models - A Multiparametric Application of MRI in Rodent Hepatic Tumor Model -- BOLD MRI Applied to a Murine Model of Peripheral Artery Disease -- Manganese-enhanced Magnetic Resonance Imaging -- Spin Echo BOLD fMRI on Songbirds -- MRI to Study Embryonic Development -- Mouse Phenotyping with MRI -- Analysis of Freshly Fixed and Museum Invertebrate Specimens using High-resolution, High-throughput MRI -- Applications of Hyperpolarized Agents in Solutions -- Target-specific Paramagnetic and Superparamagnetic Micelles for Molecular MR Imaging -- Tracking Transplanted Cells by MRI - Methods and Protocols -- MRI of CEST Based Reporter Gene | |
| 505 | 0 | 0 | |t Physical basics of NMR / |r Rolf Pohmann -- |t Spatial encoding-basic imaging sequences / |r Rolf Pohmann -- |t Basic contrast mechanisms / |r Leif Schröder and Cornelius Faber -- |t Scanner components / |r Volker C. Behr -- |t Small animal preparation and handling in MRI / |r Patrick McConville -- |t Cerebral perfusion MRI in mice / |r Frank Kober, Guillaume Duhamel, and Virginie Callot -- |t High field diffusion tensor imaging in small animals and excised tissue / |r Bernadette Erokwu, Chris Flask, and Vikas Gulani -- |t BOLD effect / |r Joan M. Greve -- |t Screening of CEST MR contrast agents / |r Xiaolei Song, Kannie W.Y. Chan, and Michael T. McMahon -- |t Hyperpolarized noble gases as contrast agents / |r Xin Zhou -- |t Hyperpolarized molecules in solution / |r Jan Henrik Ardenkjaer-Larsen . [and others] -- MR oximetry / |r Jeff F. Dunn -- |t MRI using intermolecular multiple-quantum coherences / |r Rosa Tamara Branca -- |t Experimental stroke research : the contributions of in vivo MRI / |r Therése Kallur and Mathias Hoehn -- |t Volumetry and other quantitative measurements to assess the rodent brain / |r Alize Scheenstra, Jouke Dijkstra, and Louise van der Weerd -- |t Models of neurodegenerative disease -- Alzheimer's anatomical and amyloid plaque imaging / |r Alexandra Petiet, Benoit Delatour, and Marc Dhenain -- |t MRI in animal models of psychiatric disorders / |r Dana S. Poole, Melly S. Oitzl, and Louise van der Weerd -- |t Spectroscopic imaging of the mouse brain / |r Dennis W.J. Klomp and W. Klaas Jan Renema -- |t Spinal cord -- MR of rodent models / |r Virginie Callot, Guillaume Duhamel, and Frank Kober -- |t Assessment of global cardiac function / |r Jürgen E. Schneider -- |t Plaque imaging in murine models of cardiovascular disease / |r Gert Klug, Volker Herold, and Karl-Heinz Hiller -- |t Interventional MRI in the cardiovascular system / |r Harald H. Quick -- |t MR for the investigation of murine vasculature / |r Christoph Jacoby and Ulrich Flögel -- |t MRI of the lung : non-invasive protocols and applications to small animal models of lung disease / |r Magdalena Zurek and Yannick Crémillieux -- |t Characterization of tumor vasculature in mouse brain by USPIO contrast-enhanced MRI / |r Giulio Gambarota and William Leenders -- |t Cancer models-multiparametric applications of clinical MRI in rodent hepatic tumor model / |r Feng Chen, Frederik De Keyzer, and Yicheng Ni -- |t BOLD MRI applied to a murine model of peripheral artery disease / |r Joan M. Greve -- |t Manganese-enhanced magnetic resonance imaging / |r Susann Boretius and Jens Frahm -- |t Spin echo BOLD fMRI on songbirds / |r Colline Poirier and Anne-Marie Van der Linden -- |t MRI to study embryonic development / |r Bianca Hogers -- |t Mouse phenotyping with MRI / |r X. Josette Chen and Brian J. Nieman -- |t Analysis of freshly fixed and museum invertebrate specimens using high-resolution, high-throughput MRI / |r Alexander Ziegler and Susanne Mueller -- |t Applications of hyperpolarized agents in solutions / |r Jan Henrik Ardenkjaer-Larsen [and others] -- |t Target-specific paramagnetic and superparamagnetic micelles for molecular MR imaging / |r Roel Straathof, Gustav J. Strijkers, and Klaas Nicolay -- |t Tracking transplanted cells by MRI- methods and protocols / |r Michel Modo -- |t MRI of CEST-based reporter gene / |r Guanshu Liu and Assaf A. Gilad |
| 506 | |a Restricted for use by site license | ||
| 520 | |a Nuclear magnetic resonance imaging represents a technique that is indispensable in every day biomedical diagnostics. Thanks to the numerous ways to manipulate and detect an NMR signal, it is possible to obtain a variety of information with excellent spatial and temporal resolution. Today's MRI techniques go far beyond the illustration of pure anatomical structures and include the revealing of processes down to the molecular level. The number of small animal imaging centers relying on MRI as a key method for preclinical research to understand diseases and to test for novel treatments is growing rapidly. In Vivo NMR Imaging: Methods and Protocols is written as an experimental laboratory text to provide a descriptive approach of the various applications of magnetic resonance imaging and its underlying principles. Starting from a compact introduction of basic NMR physics and image encoding techniques suitable for a broad audience in the life sciences, the concept focuses on addressing the many ways of generating contrast in MR images. The authors cover an interdisciplinary range of problems to be addressed by this non-invasive modality, including study protocols for addressing morphological, physiological, functional, and biochemical aspects of various tissues in living organisms. Information about practical aspects of designing experimental studies that follow the special conditions for micro imaging setups are also provided. Written in the successful Methods in Molecular Biology™ series format, In Vivo NMR Imaging: Methods and Protocols aims to be an experimental compendium of modern in vivo MR imaging with special focus on recent developments in molecular imaging and new protocols for imaging metabolism and molecular markers | ||
| 520 | |a Nuclear magnetic resonance imaging represents a technique that is indispensable in every day biomedical diagnostics. Thanks to the numerous ways to manipulate and detect an NMR signal, it is possible to obtain a variety of information with excellent spatial and temporal resolution. Today's MRI techniques go far beyond the illustration of pure anatomical structures and include the revealing of processes down to the molecular level. The number of small animal imaging centers relying on MRI as a key method for preclinical research to understand diseases and to test for novel treatments is growing rapidly. In Vivo NMR Imaging: Methods and Protocols is written as an experimental laboratory text to provide a descriptive approach of the various applications of magnetic resonance imaging and its underlying principles. Starting from a compact introduction of basic NMR physics and image encoding techniques suitable for a broad audience in the life sciences, the concept focuses on addressing the many ways of generating contrast in MR images. The authors cover an interdisciplinary range of problems to be addressed by this non-invasive modality, including study protocols for addressing morphological, physiological, functional, and biochemical aspects of various tissues in living organisms. Information about practical aspects of designing experimental studies that follow the special conditions for micro imaging setups are also provided. Written in the successful Methods in Molecular Biology series format, In Vivo NMR Imaging: Methods and Protocols aims to be an experimental compendium of modern in vivo MR imaging with special focus on recent developments in molecular imaging and new protocols for imaging metabolism and molecular markers | ||
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| 650 | 2 | |a Diagnostic Techniques and Procedures | |
| 650 | 2 | |a Disease Models, Animal | |
| 650 | 2 | |a Disease | |
| 650 | 2 | |a Investigative Techniques | |
| 650 | 2 | |a Magnetic Resonance Imaging | |
| 650 | 2 | |a Models, Animal | |
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| 830 | 0 | |a Methods in Molecular Biology, Methods and Protocols, |x 1064-3745 ; |v 771 | |
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