Genetics of chemotherapy response in triple negative breast cancer
By integrating data from all three methods, we found significantly more pCR patients with high mutation burden (including CNV and LOH) in homologous recombination repair genes than RD patients (83% vs 20%). With this metric, we can predict 83% of positive response and 80% of negative response based...
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Main Author: | Li, Charles |
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Corporate Author: | Yale University Yale School of Medicine |
Format: | Thesis Electronic Book |
Language: | English |
Published: |
Ann Arbor :
ProQuest Dissertations & Theses,
2017
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