Genomic instability and cancer metastasis : mechanisms, emerging themes, and novel therapeutic strategies /
Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner....
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| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cham :
Springer,
[2015]
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| Series: | Cancer metastasis (Series) ;
v. 20 |
| Subjects: | |
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Table of Contents:
- Preface.- Cancer Metastasis: Tracking and Attacking a Moving Target.- The generation, detection, and prevention of genomic instability during cancer progression and metastasis.- DNA damage response pathways in cancer predisposition and progression.- Mathematical modeling for DNA repair, carcinogenesis and cancer detection.- Animal models of metastasis.- Microenvironmental Control Of Metastatic Progression.- 7 Mechanotransduction, metastasis and genomic instability
- 8 Immunomodulation and Genomic Instability
- 9 Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
- Nanomedicine ? Nanoparticles in Cancer Imaging and Therapy
- Index
- Preface.- Cancer Metastasis: Tracking and Attacking a Moving Target.- The generation, detection, and prevention of genomic instability during cancer progression and metastasis.- DNA damage response pathways in cancer predisposition and progression.- Mathematical modeling for DNA repair, carcinogenesis and cancer detection.- Animal models of metastasis.- Microenvironmental Control Of Metastatic Progression.- 7 Mechanotransduction, metastasis and genomic instability
- 8 Immunomodulation and Genomic Instability
- 9 Synthetic Genetic Approaches in Colorectal Cancer: Exploiting and Targeting Genome Instability
- Nanomedicine? Nanoparticles in Cancer Imaging and Therapy
- Index