Peroxisome proliferator activated receptor s : from basic science to clinical applications /

Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. As a consequence, our knowledge of the role of these receptors in physiology and pathology continues to grow at a...

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Corporate Author: International Symposium on PPARs: From Basic Science to Clinical Applications Florence, Italy
Other Authors: Fruchart, J. C (Jean-Charles), 1945-
Format: Conference Proceeding Book
Language:English
Published: Dordrecht ; Boston : Milan, Italy : Houston, Tex. : Kluwer Academic Publishers ; Fondazione Giovanni Lorenzini Medical Science Foundation ; Giovanni Lorenzini Medical Foundation, [2002]
Series:Medical science symposia series ; v. 18
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111 2 |a International Symposium on PPARs: From Basic Science to Clinical Applications  |n (1st :  |d 2001 :  |c Florence, Italy) 
245 1 0 |a Peroxisome proliferator activated receptor s :  |b from basic science to clinical applications /  |c edited by J.-C. Fruchart ... [and others] 
246 1 8 |a PPARs :  |b from basic science to clinical applications 
246 3 |a Peroxisome proliferator activated receptors 
264 1 |a Dordrecht ;  |a Boston :  |b Kluwer Academic Publishers ;  |a Milan, Italy :  |b Fondazione Giovanni Lorenzini Medical Science Foundation ;  |a Houston, Tex. :  |b Giovanni Lorenzini Medical Foundation,  |c [2002] 
264 4 |c ©2002 
300 |a xvi, 172 pages :  |b illustrations ;  |c 25 cm 
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490 1 |a Medical science symposia series ;  |v v. 18 
504 |a Includes bibliographical references and index 
505 0 0 |t Structure, Function, and Molecular Mechanisms of PPAR Action --  |g 1  |t Peroxisome Proliferator Activated Receptor Alpha Coordinates Intermediary Metabolism During Fasting /   |r S. Kersten, B. Desvergne, W. Wahli --  |g 2.  |t Design, Structure, and Function of Novel PPAR Ligands /   |r T.M. Willson, M.H. Lambert, H.E. Xu --  |g 3.  |t Functions of PPAR Gamma in Macrophages and Atherosclerosis /   |r A. Chawla, C.-H. Lee, Y. Barak, D. Liao, R.M. Evans --  |t Inflammation and Atherosclerosis --  |g 4.  |t PPARs and Atherogenesis: Mediators or Modulators of the Inflammatory Response in the Vessel Wall? /   |r N. Marx --  |g 5.  |t Role of PPARs in Inflammation, Atherosclerosis, and Thrombosis /   |r A. Pilon, H. Duez, J.-C. Fruchart, B. Staels --  |g 6.  |t Effects of Thiazolidinediones on Vascular Reactivity and Endothelial Dysfunction /   |r E.S. Horton, A.E. Caballero, R. Saouaf, A. Veves --  |t PPAR[gamma] and [alpha] as Therapeutic Targets in Diabetes --  |g 7.  |t Activation of Human PPAR Subtypes by Pioglitazone /   |r H. Kimura, J. Sakamoto, S. Moriyama, H. Odaka, Y. Momose, Y. Sugiyama, H. Ikeda, H. Sawada --  |g 8.  |t PPAR[gamma] Mechanism of Action Studies /   |r S. Kliewer --  |t Animal Models to Study PPAR Functions --  |g 9.  |t The Role of PPAR[alpha] in Fatty Acid Metabolism and Hepatocarcinogenesis: Studies with PPAR[alpha]-Null Mice /   |r F.J. Gonzalez --  |t PPAR[alpha]: From Basic Science to Clinical Applications --  |g 10.  |t PPAR[alpha], Lipoprotein Metabolism, Metabolic Disease, and Atherosclerosis /   |r J.-C. Fruchart, B. Staels, P. Duriez --  |g 11.  |t PPAR[alpha] and Atherosclerosis /   |r J. Plutzky --  |g 12.  |t Regulation of CD36 by PPAR[gamma]: Pro- or Anti-atherogenic? /   |r M. Febbraio, A.M. Gotto, Jr., J. Han, A.C. Nicholson, K. Sharma, E.A. Podrez, H.F. Hoff, S.L. Hazen, J.D. Smith, D.P. Hajjar, R.L. Silverstein --  |t Lipid and Lipoprotein Metabolism and Atherosclerosis --  |g 13.  |t Anti-inflammatory Properties of High Density Lipoproteins /   |r P. Barter, P. Baker, J. Gamble, M. Vadas, K.-A. Rye --  |t The Importance of Raising HDL: From PPAR[alpha] to Clinical Implications --  |g 14.  |t The Low-HDL Syndrome: Epidemiology and Pathophysiology /   |r G. Franceschini, B. Villa, M. Gomaraschi, L. Calabresi --  |g 15.  |t Diabetes: A Growing CHD Epidemic /   |r A. Hamsten, G. Steiner --  |t Adipose Tissue, Obesity, and Diabetes --  |g 16.  |t Influence of PPARs on Muscle Lipid Metabolism and Insulin Resistance /   |r E.W. Kraegen, G.J. Cooney, J. Ye, S.M. Furler --  |g 17.  |t PPAR[gamma] in Adipogenesis and Insulin Resistance /   |r S.R. Farmer, J.K. Hamm, B.-H. Park --  |t PPAR[delta]: Function and Biology --  |g 18.  |t Pharmacology of a Selective Peroxisome Proliferator-Activated Receptor [delta] Agonist, GW501516, in Obese Dyslipidemic Primates /   |r W. Oliver, Jr., D. Sternbach, B. Hansen, T. Willson --  |t PPAR[gamma]: From Basic Science to Clinical Applications --  |g 19.  |t PPAR[gamma]: A Regulator of Growth and Differentiation /   |r S.R. Farmer, D. Prusty, R.F. Morrison, M. Moldes --  |g 20.  |t Peroxisome Proliferator Activator Receptor Gamma Agonists Inhibit the Development of Atherosclerosis in Low Density Lipoprotein Receptor-Deficient Male Mice /   |r A.C. Li, C.K. Glass --  |g 21.  |t Are Thiazolidinediones Superior to Standard Therapy in the Treatment of Type 2 Diabetes? /   |r M.-R. Taskinen --  |t Clinical Studies with PPAR Ligands --  |g 22.  |t PPAR[gamma] Ligands and Intestinal Inflammation /   |r A. Flanigan, T.A. Judge, J.D. Lewis, R.J. Stein, G.R. Lichtenstein, J.J. Deren, R. Arifuddin, S. Murthy, G.D. Wu --  |g 23.  |t Inflammatory Mechanisms in Alzheimer's Disease: [beta]-Amyloid-Stimulated Proinflammatory Responses Are Blocked by PPAR[gamma] Agonists /   |r G. Landreth, C. Combs, J.C. Karlo, S. Sundararajan. 
520 |a Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. As a consequence, our knowledge of the role of these receptors in physiology and pathology continues to grow at a fast pace and PPARs have become an interesting target for the treatment of many pathological conditions, including diabetes and atherosclerosis. This volume provides an authoritative view of the current clinical and scientific developments within this evolving area of study 
650 0 |a Nuclear receptors (Biochemistry)  |v Congresses 
650 0 |a Peroxisomes  |v Congresses 
650 0 |a Transcription factors  |v Congresses 
650 7 |a Nuclear receptors (Biochemistry)  |2 fast 
650 7 |a Peroxisomes  |2 fast 
650 7 |a Transcription factors  |2 fast 
650 1 2 |a Receptors, Cytoplasmic and Nuclear 
650 1 2 |a Transcription Factors 
655 2 |a Congress 
655 7 |a Conference papers and proceedings  |2 fast 
655 7 |a Conference papers and proceedings  |2 lcgft 
700 1 |a Fruchart, J. C  |q (Jean-Charles),  |d 1945- 
830 0 |a Medical science symposia series ;  |v v. 18 
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