Within-host evolution of HIV-1: Novel pathways of virus escape from cellular and humoral immunity /

Within-host evolution of HIV-1: Novel pathways of virus escape from cellular and humoral immunity /

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Longitudinal HIV-1 single genome sequencing (SGS), which permits unambiguous genetic characterization of circulating viral strains without introduction of PCR error, can be used to identify sites in the viral genome that are under selective pressure. Following transmission, the earliest sites under...

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Bibliographic Details
Main Author: Kreider, Edward F. (Author)
Other Authors: Doms, Robert W. (degree committee member), Hensley, Scott E. (degree committee member), Hoxie, James A. (degree committee member), Kohli, Rahul M. (degree committee member)
Format: Thesis Book
Language:English
Published: [Philadelphia, Pennsylvania] : Ann Arbor : University of Pennsylvania ; ProQuest Dissertations & Theses, 2016
Subjects:
Cell and Molecular Biology > Penn dissertations
Microbiology
Penn dissertations > Cell and Molecular Biology
Academic theses
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