Characterization of alpha-synuclein-induced vesicular accumulation in a yeast model of Parkinson's disease

The presence of alpha-synuclein protein inclusions in the brain is a central pathological hallmark of Parkinson's disease and several other neurodegenerative diseases. alpha-Synuclein is deposited in the form of amyloid fibrils in all of these diseases, and the process by which alpha-synuclein...

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Bibliographic Details
Main Author: Soper, James H
Corporate Author: University of Pennsylvania
Other Authors: Lee, V. M.-Y (Virginia M.-Y.) (advisor.)
Format: Thesis Book
Language:English
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